Koura Zephex® propellants are used in many of the world’s metered dose inhalers, helping over 100 million people with respiratory conditions such as asthma and COPD

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Our Team

Quality & Regulatory

Doctor and patient with inhalers in hand

Our Innovation

Our History

Zephex® is a brand of Koura, a company with a rich and proud history dating back almost 100 years, with solid foundations that were firmly laid in iconic industry names such as ICI, Inovyn, Ineos and Mexichem.

We are the world leader in the manufacture and supply of very high purity HFA medical propellants. Since 1995 Zephex® products have filled around 3.5 billion inhalers, helping to improve the lives of over 100 million people every year.

Produced to the most demanding industry standards at dedicated facilities, Zephex® propellants are used in around 75% of the world’s metered dose inhalers. This commitment to the highest levels of medical propellant quality is supported by a detailed understanding of customer requirements and experienced staff with many years of technical expertise.

Customer Service

The highly experienced Zephex® team provide a comprehensive range of key support services to customers as an integral part of our offering, including:

In addition to our own Certificate of Analysis, if required we can facilitate completely independent customer “acceptance testing” to analyse shipments before they are despatched.
Support in complying with ICH guidelines as confirmed by inspection bodies such as the FDA and MHRA, and in meeting other legislation such as the European F-Gas regulations.
Skilled analytical and transport engineering services to assist in the specification, design, installation and validation of propellant storage and handling facilities.
A range of technical support including formulation advice, full regulatory documentation support and analytical methods.

Innovation

Koura has developed a new, innovative low global warming potential (GWP) medical propellant, introducing Zephex 152a.

Zephex® 152a will reduce the carbon footprint of pressurised metered dose inhalers, bringing about a greater than 90 percent reduction in GWP compared to some current MDI propellants. This will mean over 100 million people with respiratory conditions such as asthma can address any concerns over the carbon footprint of their asthma inhaler.

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From the Newsroom

Efficacy, Sustainability and Longevity

As the leading manufacturer and supplier of the world’s medical propellants, a vital component within Metered Dose Inhalers (pMDI), Koura offers a product portfolio which